A young woman named Deseray Underwood has been found dead, in her London lodgings, by her finance Samuel Mortimer. The body itself shows no signs of a struggle. Lestrade, baffled by the cause of death, summons the aid of Sherlock Holmes and his great powers of deduction. Holmes stumbles upon one single clue, a crystal blue bottle, which sends him and Watson on a wild chase through the streets of London in pursuit of answers to this young woman's sudden demise. A death that would make any benefactor very wealthy.